UCLA college student Jonathan Moore (Anthony Edwards) is playing a game called "Gotcha" (popular on mid-1980s college campuses as "Assassin" or "Tag"), wherein the players are all assigned a mock "hit" on another player by use of a harmless paintball gun. Moore and his apartment roommate Manolo go on a vacation to Paris, France. After touring some of Paris, in a cafe Moore meets Sasha Banicek (Linda Fiorentino), a Czechoslovakian girl. Eventually, Jonathan has intercourse with Sasha, losing his virginity.
Jonathan decides to leave Manolo (who is heading to Spain) and go with Sasha to West Berlin to spend more time with her. Jonathan believes that he is in love with Sasha. There, Jonathan and Sasha continue to have sex and even go to an Oktoberfest beer gathering. One night, Sasha tells Jonathan that she has to go to East Berlin to pick up a package. One night after arriving in East Berlin, Sasha leaves their hotel room and walks to dark street corner. There, Sasha meets a German man who tells her the location of the pickup of her package. Meanwhile, Sasha was being monitored by a Soviet agent, who was sitting in a car at a distance. During the day, Sasha tells Jonathan that if she gives him a certain message, it means that he has to leave East Berlin immediately. At a cafe, Sasha gives Jonathan a package and says that a strudel is inside. A little later, Sasha tells Jonathan to meet her at the butcher shop near their hotel. All of a sudden, a Soviet agent begins to chase after Sasha. Sasha decides to use Jonathan (who is holding her package) to unknowingly get the package over to West Berlin. Meanwhile, Sasha is taken by the Soviet agent and East German secret police.
Jonathan goes to Checkpoint Charlie to cross the heavily fortified border into West Berlin. At the East German customs search, Jonathan is stripped of his clothes and given a cavity search. Meanwhile, Sasha is stripped and searched for possible espionage evidence. Vlad arrives at the border crossing to search for Jonathan, however Jonathan passes the border safely before he can be captured. Once in West Berlin, Jonathan feels liberated by the Westernized society. In the hotel, Jonathan receives a message from Sasha to meet him at a specified location. Jonathan finds out that his hotel room was broken into and robbed of his traveler's checks. Soviet agents eventually find Jonathan in West Berlin and chase him throughout a public park. Jonathan jumps into a water canal and manages to escape from the Soviets and stumbles upon a German rock group headed for Hamburg, who offer him a ride to the airport.
The rock group successfully get Jonathan to the airport (using full-face makeup to sneak him past a checkpoint) and Jonathan finally arrives in Los Angeles Tom Bradley International Airport and to his apartment. Soon, Vlad and a band of Soviet agents arrive too in Los Angeles. Once home, Jonathan stumbles upon a film canister, which was planted by Sasha. Jonathan visits his parents and tells them what happened in Germany but they cannot believe a word of it and think Jonathan is on drugs. Jonathan decides to call the FBI then the Central Intelligence Agency for help. Jonathan returns to find his apartment broken into and looted.
The CIA officer tells Jonathan to give them the photo film canister. At the Los Angeles headquarters of the CIA, Jonathan spots Sasha who looks like she was working there. Jonathan eventually meets up with Sasha. Sasha admits that she is Cheryl Brewster, a CIA agent, originally from Pittsburgh. Out of nowhere, Vlad and his gang begin to chase Jonathan and Cheryl on the UCLA campus. Jonathan eliminates all the Soviets with a tranquilizer gun which he gets from the campus veterinary sciences building. The Soviets are arrested, the CIA agents thank Jonathan for his (indirect) help in obtaining the film, and Sasha tells him she wants to continue their relationship.
After they part, Jonathan talks to a pretty student who rebuffs him coldly. As she walks away, he aims the tranquilizer pistol and shoots her in the rear.
温子仁利用了自己鬼片导演的人设，前半场成功的把观众倒入传统的恐怖片的模式，各种灵异现象让我们相信马上又是一次驱魔的表演。后半程画风急转，展现了温导在驾驭各种商业类型题材上的功力，血腥暴力加气氛的渲染，看的肾上腺飙升，片子本身有一些说不通的地方，但是本格手法合理解释变格剧情无大的纰漏已经是高手了，加上优质的视听效果可以有一个好的分数。个人评价8分，因为国内版本的问题打个10分拉一下偏低的豆瓣评分！
另外这部电影真的不恐怖，请放心食用，R级的程度也就只有个别画面比较血腥，与其说是恐怖片，为什么看到后面我觉得更像是动作片？还有，结局太过于突然了，警察局事件如何收场都没交代清楚，不管怎么说，强行爱与正义的收尾很不现实。
缓缓打出一个“就这”。气氛、表演还是挺到位的，真相揭晓是个什么鬼？“鬼”的动作设计得非常粗糙，演的时候各种露馅，靠的是柯南伯格式的血浆怪物来拉满的恐惧，实际上跟类似的恐怖片佳作没法比。两星半
变身后一人屠一警察局，还能控制电流是怎么个设定，没得解释啊。
近些年来看过的最好看的恐怖片，也是我觉得温子仁恐怖片里面数一数二的水平，我不懂为什么只有7.1分，如果大家把它当做一部传统的恐怖片来看的话，那可能是有那么一点点的落差，但关键这部电影根本就没有鬼，甚至还有一点温情的感觉，看到最后的时候，我甚至还有那么一点点同情百加利，而且最让我大受震撼的是，以前看的所有关于人格分裂的电影都是一个实体两个人格，《致命感应》完全不一样，把人格分裂完全的实体化，这个想法简直太牛逼了，真的是一部非常非常优秀的恐怖片！
哇晒好喜欢！！刺穿皮肉的断骨，在吊顶警局里飞舞着反打时候脑后闭着眼的女人的脸，还有一脚踩爆你的头！太喜欢了太喜欢了，完全是我喜爱的七八十年代恐怖暴力美学！就是有点在意女主这该怎么判啊……不禁感叹一句罗翔老师普法有方（。
看见警察调查文件的时候那一堆U盘，怎么总感觉温子仁又在挖大坑😂
前面还可，后面真面目出来以后...动作戏太喜感了。吴宇卫，橄榄我谢谢🙏
Blood or not, you will always be my sister.
看前面还在感慨温子仁怎么开始走下坡路了，看最后三十分钟，卧槽，不愧是你温子仁。最后的警察局大战，恍惚中以为又看到一个女版约翰威克，这战力就是让她加入DC宇宙都不成问题
❸更准确的片名应该就直译——“恶性肿瘤”的《恶性》。
感觉制作很粗糙..少了一种质感. 特别是催眠那一段是我看过最简陋的太随意了。警局杀人那里倒是挺爽的，但是最后非常突兀的就结束了把科警察晾在一边就有点不明不白的。温子仁的作品不应该是这样的 说实话有点失望电影创意还是不错的如果能再打磨一下就好了。 6.5/10
温子仁又带来了一个“脑洞大开”的恐怖片，在《招魂》《潜伏》系列日落西山的情势下开辟了一个新战场，证明了自己才气依旧。怪物的真实身份虽然不难猜出，但出色的讲故事技巧和氛围营造依然能吸引人看下去。
四星半，真正的“脑洞大开”，打斗场面暴力血腥，但只是团灭了群演，对主角下手并不是太狠。对惊悚画面心理把控的真好，尤其喜欢屋内的戏码
故事整体比较简单，就是Jump scare太多后面反而觉得没怎么被吓到…另外Gabriel开口我还以为他会说「I’d like to play a game…」🤦♂️
不错，这次看来是花了心思，而不像之前那样纯挂名的，整体可看性确实高不少，小反转做的有点刻意，不够亮。总体来说还算满意
温子仁的台词一直这么差吗？🤔 这直给到感觉作者意图从耳朵直接插入到鼻腔了。核心梗挺有意思，和风格一样复古，感觉在看七八十年代的东西。
3星半。虽然低于预期，但成片完成度非常高，故事创意也很有意思，仍然是在类型片水准之上的娱乐片。温子仁的惊悚恐怖片依然值得信赖。
难怪有翻译叫“肿瘤侠”如果第二部是用这个身份行侠仗义的话，这个翻译真的神预测。
不错，这次看来是花了心思，而不像之前那样纯挂名的，整体可看性确实高不少，小反转做的有点刻意，不够亮。总体来说还算满意
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